A-620223 (succinate)

MedChem Express

A-620223 (succinate)

14

Research Use Only

C20H28N4O5

404.46

A-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase ( PARP ) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a K i value of 8 nM and an EC 50 value of 3 nM in whole cell assay, making it useful in cancer research [1] .

CCCN(CC1)CCC1C2=NC3=C(C(N)=O)C=CC=C3N2.O=C(O)CCC(O)=O

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