A-81282
HY-101823A
Molecular Weight429.47
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameA-81282
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC23H23N7O2
- Molecular Weight429.47
- Scientific DescriptionA-81282 (Abbott 81282) is an antagonist of angiotensin IIs AT1 receptor, with a p A2 value of 9.64 at the AT1 receptor in rabbit aorta. A-81282 also demonstrates significant inhibitory action on the binding of [125i]_Sar1_lle8_Angiotensin_ll to rat liver membranes, with a p KI value of 8.505. A-81282 has antihypertensive activity and can effectively lower blood pressure in renal artery-ligated rats [1] .
- SMILESO=C(C1=CN=CN=C1N(CCCC)CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)O
- UNSPSC12352200