A 83-01 (sodium)

MedChem Express

A 83-01 (sodium)

9

Research Use Only

98.43

C25H19N5NaS

444.51

A 83-01 sodium is a potent inhibitor of TGF-beta type I receptor ALK5 kinase , ALK4 and ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1] .

S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5.[Na]

2°C to 8°C

12352200