A-849519 [904680-01-9]

TargetMol Chemicals

A-849519 [904680-01-9]

86

Chemical

A-849519

C22H25FN2O4S

432.51

A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor.

3 years

C(O)(=O)C1=C2C(=CC=C1NS(=O)(=O)C3=C(/C=C\CN(C)C)C=C(F)C=C3)CCCC2

-20°C

12352200