Bio-Connect

A1CF Polyclonal Antibody

RD266005A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetA1CF
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    A1CF Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID29974
  • Target name
    A1CF
  • Target description
    APOBEC1 complementation factor
  • Target synonyms
    ACF; ACF64; ACF65; apo-B RNA editing protein; APOBEC1 complementation factor; apobec-1 complementation factor (ACF) (ASP); APOBEC-1 stimulating protein; APOBEC1CF; ASP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203