A1CF Polyclonal Antibody
RD266005A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetA1CF
Overview
- SupplierReddot Biotech
- Product NameA1CF Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID29974
- Target nameA1CF
- Target descriptionAPOBEC1 complementation factor
- Target synonymsACF; ACF64; ACF65; apo-B RNA editing protein; APOBEC1 complementation factor; apobec-1 complementation factor (ACF) (ASP); APOBEC-1 stimulating protein; APOBEC1CF; ASP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203