AAK1-IN-4 [1815612-79-3]

MedChem Express

AAK1-IN-4 [1815612-79-3]

10

1815612-79-3

Research Use Only

C20H28N4O3

372.46

AAK1-IN-4 is a highly selective, CNS-penetrable, and orally active adaptor protein-2-associated kinase 1 (AAK1) inhibitor (AAK1 IC50 of 4.6 nM, Filt Ki of 0.9 nM, and cell IC50 of 8.6 nM). AAK1-IN-4 has the potential for the research for neuropathic pain[1].

CC(C[C@](N)(COC1=CC=C(C2=CC=NC(NC(OC)=O)=C2)N=C1C)C)C

12131703