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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using AANAT Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using AANAT Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using AANAT Polyclonal Antibody at dilution 1:40

AANAT Polyclonal Antibody

Research Use Only
E-AB-10969
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    AANAT Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • UNSPSC
    12352203