AAV6-CRE

Vector Biolabs

AAV6-CRE

5

Other Application

Research Use Only

3E12 GC/ml

This AAV serotype 6 virus (Capsid from AAV6 and ITR from AAV2) expresses Cre Recombinase under the control of a CMV promoter. This Cre contains a nuclear localization signal (NLS). Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.

-80°C

41106621