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ABBV-167

T38750
TargetMol Chemicals
CAS Number1351456-78-4
Product group Chemicals
Molecular Weight978.45
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ABBV-167
  • Delivery Days Customer
    1001
  • CAS Number
    1351456-78-4
  • Category Supplier
    Chemical
  • Chemical Name
    ABBV-167
  • Molecular Formula
    C46H53ClN7O11PS
  • Molecular Weight
    978.45
  • Scientific Description
    ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.
  • Shelf life instruction
    3 years
  • SMILES
    CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cn(COP(O)(O)=O)c4nccc4c3)c2)=C(C1)c1ccc(Cl)cc1 ;c:63;
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Salem AH, et al. Expanding the Repertoire for Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Mol Cancer Ther. 2021 Jun;20(6):999-1008."