ABC1183

MedChem Express

ABC1183

10

Research Use Only

99.19

C18H14N4OS

334.39

ABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3beta, GSK3alpha and CDK9/cyclin T1 with the IC50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activities[1].

N#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1

-20°C,2°C to 8°C

12352200