Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] (GTX82741).
ABCA4 (Rim Protein) antibody [3F4]
GTX82741
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human, Mouse, Xenopus
TargetAbca4
Overview
- SupplierGeneTex
- Product NameABCA4 (Rim Protein) antibody [3F4]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3F4
- ConjugateUnconjugated
- Gene ID11304
- Target nameAbca4
- Target descriptionATP-binding cassette, sub-family A (ABC1), member 4
- Target synonymsAbc1; Abc10; Abcr; ATP-binding cassette 10; ATP-binding cassette sub-family A member 4; AW050280; D430003I15Rik; R; retinal-specific ATP-binding cassette transporter; retinal-specific phospholipid-transporting ATPase ABCA4; RIM ABC transporter; Rim protein; RmP
- HostMouse
- IsotypeIgG
- Scientific DescriptionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein was the first of the ABC transporters to be observed in photoreceptors and may play a role in the photoresponse. Mutations in the human gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Mouse, Xenopus
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily. Illing M et al., 1997 Apr 11, J Biol ChemRead more