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Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] (GTX82741).
Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] (GTX82741).
Immunohistochemical staining of adult mouse retina showing specific immunolabeling of the ABCA4 protein using ABCA4 (Rim Protein) antibody [3F4] (GTX82741).

ABCA4 (Rim Protein) antibody [3F4]

GTX82741
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human, Mouse, Xenopus
TargetAbca4
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Overview

  • Supplier
    GeneTex
  • Product Name
    ABCA4 (Rim Protein) antibody [3F4]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Optimal working dilutions should be determined experimentally by the end user.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3F4
  • Conjugate
    Unconjugated
  • Gene ID11304
  • Target name
    Abca4
  • Target description
    ATP-binding cassette, sub-family A (ABC1), member 4
  • Target synonyms
    Abc1; Abc10; Abcr; ATP-binding cassette 10; ATP-binding cassette sub-family A member 4; AW050280; D430003I15Rik; R; retinal-specific ATP-binding cassette transporter; retinal-specific phospholipid-transporting ATPase ABCA4; RIM ABC transporter; Rim protein; RmP
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDO35600
  • Protein Name
    Retinal-specific ATP-binding cassette transporter
  • Scientific Description
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein was the first of the ABC transporters to be observed in photoreceptors and may play a role in the photoresponse. Mutations in the human gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Human, Mouse, Xenopus
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes.
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  • The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily. Illing M et al., 1997 Apr 11, J Biol Chem
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