ABCD4 antibody

GeneTex

ABCD4 antibody

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.89 mg/ml

Unconjugated

ABCD4

ATP binding cassette subfamily D member 4

69 kDa peroxisomal ABC-transporter; ABC41; ATP-binding cassette sub-family D member 4; ATP-binding cassette, sub-family D (ALD), member 4; EST352188; lysosomal cobalamin transporter ABCD4; MAHCJ; P70R; P79R; peroxisomal membrane protein 69; PMP69; PMP70-related protein; PXMP1L; PXMP1-L

Rabbit

IgG

ATP-binding cassette sub-family D member 4

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203