ABD957

MedChem Express

ABD957

5

Research Use Only

99.46

C27H36F3N7O5S

627.68

ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, with an IC 50 of 0.21 microM for ABHD17B . ABD957 can block N-Ras signaling and the growth of NRAS-mutant AML cells [1] .

C[C@H]1CN(CCN1C(N2C=CC(S(=O)(N(C)C)=O)=N2)=O)CC3=C(C=C(C=C3)C(F)(F)F)N4C5CCC4CN(C5)CC(O)=O

-20°C,2°C to 8°C

12352200