Abemaciclib-d8

MedChem Express

Abemaciclib-d8 [2088650-53-5]

10

2088650-53-5

Research Use Only

99.57

C27H24D8F2N8

514.64

Abemaciclib-d 8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

CC1=NC2=C(C=C(C=C2N1C(C)C)C3=NC(NC4=NC=C(C=C4)CN5C([2H])(C([2H])(N(C([2H])(C5([2H])[2H])[2H])CC)[2H])[2H])=NC=C3F)F

-20°C,2°C to 8°C

12352200