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Immunohistochemistry of paraffin-embedded Rat lung using Abeta40 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Rat lung using Abeta40 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Rat lung using Abeta40 Polyclonal Antibody at dilution of 1:50

Abeta40 Polyclonal Antibody

Research Use Only
E-AB-40070
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    Abeta40 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    Abeta derives from APP via proteolytic cleavage by proteases called alpha-, beta- and gamma-secretase. The alpha-secretase cleavage precludes the formation of Abeta, while the beta- and gamma-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
  • UNSPSC
    12352203