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ABT-072 potassium trihydrate

ABT-072 potassium trihydrate

Research Use Only
T38510
TargetMol Chemicals
CAS Number1132940-31-8
Product group Chemicals
Molecular Weight562.7
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ABT-072 potassium trihydrate
  • Delivery Days Customer
    14
  • CAS Number
    1132940-31-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    ABT-072 potassium trihydrate
  • Molecular Formula
    C24H33KN3O8S
  • Molecular Weight
    562.7
  • Scientific Description
    ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).
  • Shelf life instruction
    3 years
  • SMILES
    O.O.O.[K].COc1c(\C=C\c2ccc(NS(C)(=O)=O)cc2)cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Shi Y, et al. Assessing Supersaturation and Its Impact on In Vivo Bioavailability of a Low-Solubility Compound ABT-072 With a Dual pH, Two-Phase Dissolution Method. J Pharm Sci. 2016;105(9):2886-2895.
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