ABT-263 (Navitoclax) [923564-51-6]

Biorbyt

ABT-263 (Navitoclax) [923564-51-6]

16

923564-51-6

Research Use Only

C47H55CLF3N5O6S3

974.6127

ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.

ClC1C([H])=C([H])C(=C([H])C=1[H])C1C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C=1C([H])([H])N1C([H])([H])C([H])([H])N(C2C([H])=C([H])C(C(N([H])S(C3C([H])=C([H])C(=C(C=3[H])S(C(F)(F)F)(=O)=O)N([H])[C@@]([H])(C([H])([H])SC3C([H])=C([H

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