ABT-737 [852808-04-9]

Biorbyt

ABT-737 [852808-04-9]

16

852808-04-9

Research Use Only

C42H45CLN6O5S2

813.4269

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively.

ClC1C([H])=C([H])C(=C([H])C=1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2C([H])=C([H])C(C(N([H])S(C3C([H])=C([H])C(=C(C=3[H])[N+](=O)[O-])N([H])[C@@]([H])(C([H])([H])SC3C([H])=C([H])C([H])=C([H])C=3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(=O)=O)=O)=C([H])C=2[H])C([H])([H])C1([H])[H]

12352200