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ABT-737 [852808-04-9]

Research Use Only
S1002
Selleck Chemicals
CAS Number852808-04-9
Product group Chemicals

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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    ABT-737 [852808-04-9]
  • Delivery Days Customer
    9
  • CAS Number
    852808-04-9
  • Certification
    Research Use Only
  • Scientific Description
    ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosis and mitophagy. Phase 2.
  • UNSPSC
    12352200

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