ABT-737 [852808-04-9]
S1002
CAS Number852808-04-9
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameABT-737 [852808-04-9]
- Delivery Days Customer9
- CAS Number852808-04-9
- CertificationResearch Use Only
- Scientific DescriptionABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosis and mitophagy. Phase 2.
- UNSPSC12352200
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