Abz-GIVRAK(Dnp)

MedChem Express

Abz-GIVRAK(Dnp)

14

Research Use Only

C41H61N13O12

928.00

Abz-GIVRAK(Dnp) is the most efficient substrate for cathepsin B and is highly selective for this enzyme among lysosomal cysteine proteases. After Abz-GIVRAK(Dnp) is hydrolyzed, aminoacylbenziminosulfosuccinic acid (Abz-SAS) is released, and dinitrobenzoyl (Dnp) is also released. The product of this hydrolysis reaction, Abz-SAS, is fluorescent under ultraviolet light and can emit a fluorescent signal[1].

O=C(C1=C(C=CC=C1)N)NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](C(O)=O)CCCCNC2=C(C=C(C=C2)[N+]([O-])=O)[N+]([O-])=O)=O)=O)=O)=O)=O

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