ACT-462206

MedChem Express

ACT-462206 [1361321-96-1]

10

1361321-96-1

Research Use Only

99.60

C20H24N2O4S

388.48

ACT-462206 is an orally active and potent dual Orexin 1 / Orexin 2 receptor antagonist with IC 50 s of 60 nM ( Orexin 1 ) and 11 nM ( Orexin 2 ), respectively. ACT-462206 exhibits brain penetration properties, and can be used for insomnia, stress/anxiety-related disorders and addiction research [1] .

O=C([C@H]1N(S(=O)(C2=CC=C(OC)C=C2)=O)CCC1)NC3=CC(C)=CC(C)=C3

2°C to 8°C

12352200