Bio-Connect

Actin Antibody (pan muscle)

ORB248619
Biorbyt
TargetACTA1
Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Actin Antibody (pan muscle)
  • Delivery Days Customer
    16
  • Application Supplier Note
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Muscle actin HHF35 antibody to be titered up or down for optimal performance.1. No special pretreatment is required for the IHC staining of formalin-fixed, paraffin-embedded tissues.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
  • Applications Supplier
    Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT IHC-P, WB
  • Clone ID
    HHF35
  • Gene ID58
  • Target name
    ACTA1
  • Target description
    actin alpha 1, skeletal muscle
  • Target synonyms
    ACTA; actin, alpha skeletal muscle; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM
  • Protein IDP62736
  • Protein Name
    Actin, aortic smooth muscle
  • Scientific Description
    This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. This mAb recognizes alpha and gamma isotypes of all muscle groups. Nonmuscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of nonmuscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203