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Actinonin [13434-13-4]

Research Use Only
A0978
LKT Laboratories
Product group Chemicals
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Actinonin [13434-13-4]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    Peptide deformylase, MMP meprin A, aminopeptidase N (CD13) inhibitor.; Actinonine
  • UNSPSC
    12352200

References

  • Sheth A, Escobar-Alvarez S, Gardner J, et al. Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers. Cell Death Dis. 2014 Mar 27;5:e1152. PMID: 24675470. Goemaere E, Melet A, Larue V, et al. New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity. J Antimicrob Chemother. 2012 Jun;67(6):1392-400. PMID: 22378679. Wang Z, Herzog C, Kaushal GP, et al. Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis. Shock. 2011 Feb;35(2):141-7. PMID: 20577148. Sharma A, Sharma S, Khuller GK, et al. In vitro and ex vivo activity of peptide deformylase inhibitors against Mycobacterium tuberculosis H37Rv. Int J Antimicrob Agents. 2009 Sep;34(3):226-30. PMID: 19505802. Sina A, Lord-Dufour S, Annabi B. Cell-based evidence for aminopeptidase N/CD13 inhibitor actinonin targeting of MT1-MMP-mediated proMMP-2 activation. Cancer Lett. 2009 Jul 8;279(2):171-6. PMID: 19264392.