ACTN2 Polyclonal Antibody

Reddot Biotech

ACTN2 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot

Research Use Only

1 mg/ml

Unconjugated

ACTN2

actinin alpha 2

alpha-actinin skeletal muscle; alpha-actinin-2; CMD1AA; CMH23; F-actin cross-linking protein; MPD6; MYOCOZ; truncated actinin alpha 2

Rabbit

IgG

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C

12352203