The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA616041(ACY1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
ACY1 Antibody
CSB-PA616041
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetACY1
Overview
- SupplierCusabio
- Product NameACY1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID95
- Target nameACY1
- Target descriptionaminoacylase 1
- Target synonymsACY-1; ACY1D; acylase; aminoacylase-1; epididymis secretory protein Li 5; HEL-S-5; N-acyl-L-amino-acid amidohydrolase
- HostRabbit
- IsotypeIgG
- Protein IDQ03154
- Protein NameAminoacylase-1
- Scientific DescriptionThis gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203