ADAM10 antibody [7H12]

GeneTex

ADAM10 antibody [7H12]

9

Weak cross reactivity is observed to ADMA9 and ADMA15 in western blotting.

WB: 1:500 - 1:1000. ICC/IF: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

7H12

500 ug/ml

Unconjugated

Adam10

a disintegrin and metallopeptidase domain 10

1700031C13Rik; a disintegrin and metalloprotease domain (ADAM) 10; disintegrin and metalloproteinase domain-containing protein 10; kuz; kuzb; kuzbanian; kuzbanian protein homolog; MADM; mammalian disintegrin-metalloprotease

Rat

IgG2

Disintegrin and metalloproteinase domain-containing protein 10

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that is involved in the proteolytic release of membrane-bound proteins in a process called ectodomain shedding. Mice lacking the encoded protein die in utero with multiple defects of the developing central nervous system, somites, and cardiovascular system. [provided by RefSeq, May 2016]

Mouse

-20°C or -80°C,2°C to 8°C

12352203