ADAMTS2 Polyclonal Antibody

Reddot Biotech

ADAMTS2 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

Adamts2

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2

A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin and metalloproteinase with thrombospondin repeats; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM-; ADAM-TS 2; ADAM-TS2; ADAMTS-2; hP; PC I-NP; PCINP; pNPI; procollagen I/II amino propeptide-processing enzyme; procollagen N-endopeptidase; procollagen N-proteinase

Rabbit

IgG

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Human, Mouse, Rat

-20°C

12352203