ADAMTS4 antibody, PAb
ORB47950
ApplicationsWestern Blot
Product group Antibodies
ReactivityCanine, Human, Mouse, Rabbit, Rat
Overview
- SupplierBiorbyt
- Product NameADAMTS4 antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWestern blot - 0.1-0.5 μg/ml - Human, Mouse, Rat - - - WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit Polyclonal to ADAMTS4. ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
- ReactivityCanine, Human, Mouse, Rabbit, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203