![ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein at cytosol(secreted) on SkHep1xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep1xenograft. ADAMTSL2 antibody [C3], C-term (GTX102069) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein at cytosol(secreted) on SkHep1xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep1xenograft. ADAMTSL2 antibody [C3], C-term (GTX102069) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min](https://www.genetex.com/upload/website/prouct_img/normal/GTX102069/GTX102069_39911_IHC_w_23060100_477.webp)
ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein at cytosol(secreted) on SkHep1xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep1xenograft. ADAMTSL2 antibody [C3], C-term (GTX102069) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min
ADAMTSL2 antibody [C3], C-term
GTX102069
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetADAMTSL2
Overview
- SupplierGeneTex
- Product NameADAMTSL2 antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9719
- Target nameADAMTSL2
- Target descriptionADAMTS like 2
- Target synonymsADAMTSL-2, GPHYSD1, ADAMTS-like protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ86TH1
- Protein NameADAMTS-like protein 2
- Scientific DescriptionThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li S, Tao W, Huang Z, et al. The Transcriptional Landscapes and Key Genes in Brain Arteriovenous Malformation Progression in a Venous Hypertension Rat Model Revealed by RNA Sequencing. J Inflamm Res. 2022,15:1381-1397. doi: 10.2147/JIR.S347754Read this paper
- Piccolo P, Sabatino V, Mithbaokar P, et al. Geleophysic dysplasia: novel missense variants and insights into ADAMTSL2 intracellular trafficking. Mol Genet Metab Rep. 2019,21:100504. doi: 10.1016/j.ymgmr.2019.100504Read this paper
- Aviram R, Zaffryar-Eilot S, Hubmacher D, et al. Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families. Matrix Biol. 2019,75-76:114-125. doi: 10.1016/j.matbio.2018.05.003Read this paper
- Hubmacher D, Wang LW, Mecham RP, et al. Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015,8(5):487-99. doi: 10.1242/dmm.017046Read this paper
![HepG2 whole cell extract and conditioned medium (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. HepG2 whole cell extract and conditioned medium (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX102069/GTX102069_39911_20240105_WB_Fraction_24011618_460.webp)
![ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein by immunohistochemical analysis. Sample: Paraffin-embedded rat tissues. ADAMTSL2 stained by ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min ADAMTSL2 antibody [C3], C-term detects ADAMTSL2 protein by immunohistochemical analysis. Sample: Paraffin-embedded rat tissues. ADAMTSL2 stained by ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX102069/GTX102069_39911_20240301_IHC-P_multiple_R_24030600_763.webp)
![C2Cl2 whole cell and differentiated extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. C2Cl2 whole cell and differentiated extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with ADAMTSL2 antibody [C3], C-term (GTX102069) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX102069/GTX102069_45341_20240308_WB_M_Differentiated_24052202_116.webp)



![C2C12 whole cell and differentiated (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ADAMTSL2 antibody [HL2616] (GTX639070) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639070/GTX639070_T-45173_20240126_WB_M_Differentiated_24013018_537.webp)




