Bio-Connect

ADAR2 antibody

GTX114237
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetADARB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    ADAR2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID104
  • Target name
    ADARB1
  • Target description
    adenosine deaminase RNA specific B1
  • Target synonyms
    ADAR2; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase DRADA2; NEDHYMS; RED1; RNA editing deaminase 1; RNA-editing enzyme 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP78563
  • Protein Name
    Double-stranded RNA-specific editase 1
  • Scientific Description
    This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. Freund EC et al., 2020 May 19, Cell Rep
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  • Androgen receptor-regulated circFNTA activates KRAS signaling to promote bladder cancer invasion. Chen J et al., 2020 Apr 3, EMBO Rep
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  • Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Wang Y et al., 2017 Jul, Genome Res
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  • Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Shoshan E et al., 2015 Mar, Nat Cell Biol
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