ADAR2 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX114237
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetADARB1
Overview
- SupplierGeneTex
- Product NameADAR2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID104
- Target nameADARB1
- Target descriptionadenosine deaminase RNA specific B1
- Target synonymsADAR2; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase DRADA2; NEDHYMS; RED1; RNA editing deaminase 1; RNA-editing enzyme 1
- HostRabbit
- IsotypeIgG
- Protein IDP78563
- Protein NameDouble-stranded RNA-specific editase 1
- Scientific DescriptionThis gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. Freund EC et al., 2020 May 19, Cell RepRead more
- Androgen receptor-regulated circFNTA activates KRAS signaling to promote bladder cancer invasion. Chen J et al., 2020 Apr 3, EMBO RepRead more
- Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Wang Y et al., 2017 Jul, Genome ResRead more
- Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Shoshan E et al., 2015 Mar, Nat Cell BiolRead more