ADAR2 antibody
GTX114237
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetADARB1
Overview
- SupplierGeneTex
- Product NameADAR2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID104
- Target nameADARB1
- Target descriptionadenosine deaminase RNA specific B1
- Target synonymsADAR2, DRABA2, DRADA2, NEDHYMS, RED1, double-stranded RNA-specific editase 1, RNA editing deaminase 1, RNA-editing enzyme 1, adenosine deaminase, RNA-specific, B1 (homolog of rat RED1), dsRNA adenosine deaminase DRADA2
- HostRabbit
- IsotypeIgG
- Protein IDP78563
- Protein NameDouble-stranded RNA-specific editase 1
- Scientific DescriptionThis gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Freund EC, Sapiro AL, Li Q, et al. Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. Cell Rep. 2020,31(7):107656. doi: 10.1016/j.celrep.2020.107656Read this paper
- Chen J, Sun Y, Ou Z, et al. Androgen receptor-regulated circFNTA activates KRAS signaling to promote bladder cancer invasion. EMBO Rep. 2020,21(4):e48467. doi: 10.15252/embr.201948467Read this paper
- Wang Y, Xu X, Yu S, et al. Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Genome Res. 2017,27(7):1112-1125. doi: 10.1101/gr.219741.116Read this paper
- Shoshan E, Mobley AK, Braeuer RR, et al. Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nat Cell Biol. 2015,17(3):311-21. doi: 10.1038/ncb3110Read this paper





