ADENOVIRUS-CBR
1283
ApplicationsOther Application
Product group Expression
Overview
- SupplierVector Biolabs
- Product NameADENOVIRUS-CBR
- Delivery Days Customer5
- ApplicationsOther Application
- CertificationResearch Use Only
- Concentration1E10 PFU/ml
- Scientific DescriptionAdenomatous polyposis coli gene (APC) is a tumor suppressor gene located on chromosome 5q2. It is inactivated in most colorectal tumors. APC is a cytoplasmic protein that can bind to and promote the degradation of b-catenin. In most colorectal tumors, APC is inactivated. This increases the interaction between b-catenin and Tcf family of transcription factors, leading to increase transcription of genes such as c-Myc. This adenovirus contains APC mini-me fragment. Shih IM., et al., Cancer Res. 2000 Mar 15;60(6):1671-6.
- Storage Instruction-80°C
- UNSPSC41106621