ADIPOQ Antibody

Cusabio

ADIPOQ Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-a by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. Yamauchi T., Kamon J., Waki H. Kadowaki T.Nat. Med. 7:941-946(2001) Richards A.A., Stephens T., Charlton H.K. Mol. Endocrinol. 20:1673-1687(2006)

Human, Mouse, Rat

-20°C or -80°C

12352203