Western Blot analysis of Human lung cancer tissue using ADRA1B Polyclonal Antibody at dilution of 1:550
Western Blot analysis of Human lung cancer tissue using ADRA1B Polyclonal Antibody at dilution of 1:550
ADRA1B Polyclonal Antibody
E-AB-12279
Product group Antibodies
Overview
- SupplierElabscience
- Product NameADRA1B Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionAlpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
- UNSPSC12352203