ADRM1 Polyclonal Antibody

Reddot Biotech

ADRM1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.54 mg/ml

Unconjugated

ADRM1

ADRM1 26S proteasome ubiquitin receptor

110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; ARM1; ARM-1; GP110; M(r) 110,000 surface antigen; proteasomal ubiquitin receptor ADRM1; proteasome regulatory particle non-ATPase 13; proteasome ubiquitin receptor; PSMD16; rpn13 homolog

Rabbit

IgG

The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

Human, Mouse, Rat

-20°C

12352203