ADSL antibody [AT16C10]

GeneTex

ADSL antibody [AT16C10]

9

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

AT16C10

1 mg/ml

Unconjugated

ADSL

adenylosuccinate lyase

AMPS, ASASE, ASL, adenylosuccinate lyase, adenylosuccinase

Mouse

IgG1

Adenylosuccinate lyase

The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]

Human

-20°C or -80°C,2°C to 8°C

41116161