AF-DX 384 (methanesulfonate)

MedChem Express

AF-DX 384 (methanesulfonate) [118290-27-0]

14

118290-27-0

Research Use Only

C28H42N6O5S

574.74

AF-DX 384 (methanesulfonate) is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors (Kis=6.03 and 10 nM, respectively)[1]. AF-DX 384 (methanesulfonate) reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine[2].

O=C(N1C2=NC=CC=C2NC(C3=CC=CC=C31)=O)NCCN4C(CN(CCC)CCC)CCCC4.CS(=O)(O)=O

12352200