AF488 Anti-Human CD32 Antibody

Reddot Biotech

AF488 Anti-Human CD32 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

IV-3

AlexaFluor 488

FCGR2A

Fc fragment of IgG receptor IIa

CD32; CD32A; CDw32; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc gamma receptor RIIa3; FCG2; fc-gamma-RIIa; FcGR; FCGR2; FCGR2A1; fcRII-a; IGFR2; igG Fc receptor II-a; Immunoglobulin G Fc receptor II; low affinity immunoglobulin gamma Fc region receptor II-a

Mouse

IgG2b

CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcOe≥RII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Human

2°C to 8°C

12352203