Bio-Connect

AF488 Anti-Human CD32 Antibody

Research Use Only
RD20901F
Reddot Biotech
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetFCGR2A
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Reddot Biotech
  • Product Name
    AF488 Anti-Human CD32 Antibody
  • Delivery Days Customer
    5
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    IV-3
  • Conjugate
    AlexaFluor 488
  • Gene ID2212
  • Target name
    FCGR2A
  • Target description
    Fc fragment of IgG receptor IIa
  • Target synonyms
    CD32; CD32A; CDw32; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc gamma receptor RIIa3; FCG2; fc-gamma-RIIa; FcGR; FCGR2; FCGR2A1; fcRII-a; IGFR2; igG Fc receptor II-a; Immunoglobulin G Fc receptor II; low affinity immunoglobulin gamma Fc region receptor II-a
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcOe≥RII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203