AF647 Anti-Human CD27 Antibody

Reddot Biotech

AF647 Anti-Human CD27 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

O323

AlexaFluor 647

CD27

CD27 molecule

CD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7

Mouse

IgG1

CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-kappaB and SAPK/JNK activation.

Human

2°C to 8°C

12352203