More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Afatinib (BIBW2992)

Afatinib (BIBW2992)

Research Use Only
ORB154707
Biorbyt
CAS Number439081-18-2
Product group Chemicals
Molecular Weight485.9384
Price on request
Packing Size
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Biorbyt
  • Product Name
    Afatinib (BIBW2992) [439081-18-2]
  • Delivery Days Customer
    16
  • CAS Number
    439081-18-2
  • Certification
    Research Use Only
  • Molecular Formula
    C24H25N5O3FCL
  • Molecular Weight
    485.9384
  • Scientific Description
    BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
  • SMILES
    CN(C)C\C=C\C(=O)NC1=C(OC2COCC2)C=C3C(=C1)C(=NC=N3)NC4C=C(Cl)C(F)=CC=4
  • UNSPSC
    12352200