Bio-Connect

Afatinib impurity 11

HY-133780
MedChem Express
CAS Number1402086-20-7
Product group Chemicals
Estimated Purity99.10
Molecular Weight428.84
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Afatinib impurity 11 [1402086-20-7]
  • Delivery Days Customer
    10
  • CAS Number
    1402086-20-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.10
  • Molecular Formula
    C21H18ClFN4O3
  • Molecular Weight
    428.84
  • Scientific Description
    Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].
  • SMILES
    O=C(NC1=C(C=C2C(C(NC3=CC(Cl)=C(C=C3)F)=NC=N2)=C1)O[C@H]4CCOC4)C=C
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200