AFViolet 450 Anti-Rat CD45 Antibody

Reddot Biotech

AFViolet 450 Anti-Rat CD45 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

OX-1

Other Conjugate

Ptprcap

protein tyrosine phosphatase, receptor type, C polypeptide-associated protein

AI605264; CD-45-; CD-45-AP; CD45-AP; CD45-associated protein; LPAP; LSM; LSM-1; protein tyrosine phosphatase receptor type C-associated protein; PTPRC-associated protein

Mouse

IgG1

CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells?in vitro.

Rat

2°C to 8°C

12352203