AG-7404

Biorbyt

AG-7404

10

Research Use Only

98.00%

C26H29N5O7

523.54

AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 microM. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 microM, compared to values ranging from 0.202 to 0.407 microM for the V-073-susceptible parental strains.

[C@@H](C(N[C@@H](C[C@H]1C(=O)NCC1)/C=C/C(OCC)=O)=O)(CC#C)N2C(=O)C(NC(=O)C3=NOC(C)=C3)=CC=C2

-20°C

12352200