Agelasine D [92664-80-7]

AdipoGen Life Sciences

Agelasine D

10

92664-80-7

Research Use Only

>97%

C26H40N5

422.6

Antifouling compound. Antimycobacterial and antibacterial agent. Exerts its antibacterial effect by inhibiting enzyme BCG 3185c, a suspected dioxygenase thereby disrupting bacterial homeostasis. Associated with contractive responses of smooth muscles and inhibition of Na+/K+ ATPase. Cytotoxic/Antineoplastic agent. Found to exhibit inhibitory activity against several cancer cell lines, including the drug resistant renal cancer cell line (ACHN). Suppressor of RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1, NF-kappaB and ERK. Antiprotozoal compound. - Chemical. CAS: 92664-80-7. Formula: C26H40N5. MW: 422.6. Isolated from sponge Agelas sp. Antifouling compound. Antimycobacterial and antibacterial agent. Exerts its antibacterial effect by inhibiting enzyme BCG 3185c, a suspected dioxygenase thereby disrupting bacterial homeostasis. Associated with contractive responses of smooth muscles and inhibition of Na+/K+ ATPase. Cytotoxic/Antineoplastic agent. Found to exhibit inhibitory activity against several cancer cell lines, including the drug resistant renal cancer cell line (ACHN). Suppressor of RANKL-induced osteoclastogenesis via down-regulation of c-Fos, NFATc1, NF-kappaB and ERK. Antiprotozoal compound.

C/C(CC[C@H]1C(CC[C@]2([H])[C@]1(C)CCCC2(C)C)=C)=C\C[NH]3CN(C)C4=C3C(N)=NC=N4

-20°C,2°C to 8°C

12352200