Agomelatine (hydrochloride) [1176316-99-6]

MedChem Express

Agomelatine (hydrochloride) [1176316-99-6]

10

1176316-99-6

Research Use Only

99.98

C15H18ClNO2

279.76

Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively[1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively[2].

CC(NCCC1=C2C=C(OC)C=CC2=CC=C1)=O.Cl

2°C to 8°C

12352200