AH22921

MedChem Express

AH22921

9

Research Use Only

C29H35NO5

477.59

AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.

OC(CCC/C=C/C[C@H]1[C@H](N2CCOCC2)C(C[C@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)=O)=O

12352200