IK-175

MedChem Express

AHR antagonist 5 (free base) [2247950-42-9]

10

2247950-42-9

Research Use Only

99.56

C25H24FN7

441.50

IK-175 is a selective and orally active aryl hydrocarbon receptor (AHR) inhibitor. IK-175 effectively blocks AHR from translocating from the cytoplasm to the nucleus. IK-175 is highly selective for AHR over other receptors, transporters, and kinases [1] .

CC(C)C(C=N1)=C2N1C(N[C@H]3CC4=C(CC3)NC5=CC=CC=C45)=NC(C6=CN=CC(F)=C6)=N2

-20°C,2°C to 8°C

12352200