Bio-Connect

AIFM1 Polyclonal Antibody

RD70139A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityRat
TargetAifm1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    AIFM1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID83533
  • Target name
    Aifm1
  • Target description
    apoptosis inducing factor, mitochondria associated 1
  • Target synonyms
    Aif; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor 1, mitochondrial-like; apoptosis-inducing factor, mitochondrion-associated 1; Pdcd8; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
  • Reactivity
    Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203