AIFM1 Polyclonal Antibody
RD70139A
ApplicationsWestern Blot
Product group Antibodies
ReactivityRat
TargetAifm1
Overview
- SupplierReddot Biotech
- Product NameAIFM1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID83533
- Target nameAifm1
- Target descriptionapoptosis inducing factor, mitochondria associated 1
- Target synonymsAif; apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor 1, mitochondrial-like; apoptosis-inducing factor, mitochondrion-associated 1; Pdcd8; programmed cell death 8 (apoptosis-inducing factor); programmed cell death protein 8
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
- ReactivityRat
- Storage Instruction-20°C
- UNSPSC12352203