AK-1 [330461-64-8]
A4000
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameAK-1 [330461-64-8]
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionSIRT2 inhibitor.; SIRT2 inhibitor II
- UNSPSC12352200
References
- Cheon MG, Kim W, Choi M, et al. AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells. Cancer Lett. 2015 Jan 28;356(2 Pt B):637-45. PMID: 25312940. Spires-Jones TL, Fox LM, Rozkalne A, et al. Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia. Front Pharmacol. 2012 Mar 12;3:42. PMID: 22416232.