AKAP12 antibody

GeneTex

AKAP12 antibody

9

WB: 2-5 microg/ml. IP: 2-5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot

Research Use Only

Polyclonal

Unconjugated

Akap12

A-kinase anchoring protein 12

A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; A-kinase anchor protein 12; SSeCKS, Gravin, AKAP250

Sheep

IgG

A-kinase anchor protein 12

SSeCKS (Src Suppressed C Kinase Substrate) is a major protein kinase C substrate with tumor suppressor activity in models of src- and ras-induced oncogenic transformation. SSeCKS regulates actin-based cytoskeletal and tissue architecture, as well as kinases such as protein kinase C (PKC), protein kinase A (PKA) and calmodulin. Additionally, SSeCKS, has been implicated in the formation of migratory processes and cell migration during embryogenesis. Rat SSeCKS shares extensive homology with human Gravin, an autoantigen in myasthenia gravis that encodes kinase scaffolding functions and whose expression pattern in fibroblasts and nerves suggests a role in cell motility.

Rat

-20°C or -80°C,2°C to 8°C

12352203