AKT-IN-12
HY-147513
Molecular Weight722.89
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameAKT-IN-12
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC42H46N2O7S
- Molecular Weight722.89
- Scientific DescriptionAKT-IN-12 (compound 3e) is a potent Akt kinase inhibitor with an IC50 value of 0.55 microM. AKT-IN-12 induces G0/G1 cell cycle arrest and apoptosis. AKT-IN-12 also inhibits p-AKT, p-ERK, and activates p-JNK, JNK. AKT-IN-12 can be used for researching leukemia[1].
- SMILES[H][C@@]12CC3=CC=C(OC4=CC(C[C@]5(C6=C(C(OC(C7CCCS7)=O)=C(C=C6CCN5C)OC)OC8=C(C=C(C2=C8)CCN1C)OC)[H])=CC=C4OC)C=C3
- UNSPSC12352200