Bio-Connect

AKT-IN-12

Research Use Only
HY-147513
MedChem Express
Molecular Weight722.89
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AKT-IN-12
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C42H46N2O7S
  • Molecular Weight
    722.89
  • Scientific Description
    AKT-IN-12 (compound 3e) is a potent Akt kinase inhibitor with an IC50 value of 0.55 microM. AKT-IN-12 induces G0/G1 cell cycle arrest and apoptosis. AKT-IN-12 also inhibits p-AKT, p-ERK, and activates p-JNK, JNK. AKT-IN-12 can be used for researching leukemia[1].
  • SMILES
    [H][C@@]12CC3=CC=C(OC4=CC(C[C@]5(C6=C(C(OC(C7CCCS7)=O)=C(C=C6CCN5C)OC)OC8=C(C=C(C2=C8)CCN1C)OC)[H])=CC=C4OC)C=C3
  • UNSPSC
    12352200